A Case Series Study on Complications After Breast Augmentation with Macrolane™

The use of Macrolane seems to have several advantages compared to the other
standard methods for breast augmentation: it is faster, less invasive and requires only
local anaesthesia.
Nevertheless, various complications associated to the use of Macrolane have been
described, e.g. the finding of encapsulated lumps in breast tissue, infection and
parenchymal fibrosis.
The aim of this case series study is to report the results of the clinical and imaging
evaluation of the patients who came to our attention after breast augmentation with
Macrolane injection, in order to evaluate the influence of this treatment on breast
cancer screening procedures.
Between September 2009 and July 2010, seven patients, treated elsewhere with
intramammary Macrolane injection for cosmetic purposes, presented to our institution
complaining breast pain of different entity.
In all patients, Macrolane was injected under local anaesthesia in the retro-mammary
space, through a surgical cannula.
On the mammography, nodules appeared as gross lobulated radiopacities with
polycyclic contours.
On breast ultrasound, they showed hypo-anechogenic cyst-like features. In all cases,