The effect of 6-dimethylaminopurine (6-DMAP) on DNA synthesis in activated mammalian oocytes
Articolo
Data di Pubblicazione:
1996
Citazione:
The effect of 6-dimethylaminopurine (6-DMAP) on DNA synthesis in activated mammalian oocytes / Ledda, Sergio; Loi, P; Bogliolo, Luisa; Moor, Rm; Fulka, Jr. - In: ZYGOTE. - ISSN 0967-1994. - 4 (1):1(1996), pp. 7-9.
Abstract:
Mouse, sheep and bovine metaphase II oocytes were briefly preincubated in medium with 6-dimethylaminopurine (6-DMAP) and thereafter activated with ethanol before further culture in 6-DMAP supplemented medium. The presence of 6-DMAP enhances the efficiency of activation and the speed of pronuclear formation but has no effect on DNA synthesis. These results are discussed in the context of recently published data showing that the preincubation of condensed chromosomes with 6-DMAP blocks DNA synthesis when nuclei become reformed.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Mammalian oocyte; 6- DMAP; Dna synthesis
Elenco autori:
Ledda, Sergio; Loi, P; Bogliolo, Luisa; Moor, Rm; Fulka, Jr
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