Implant-Prosthetic Rehabilitation of a Patient With EEC Syndrome Using Additively Manufactured Custom-Made Subperiosteal Implants: A Case Report

Ectrodactyly-ectodermal dysplasia-cleft (EEC) syndrome is a rare genetic disorder presenting significant challenges for dental rehabilitation due to severe maxillary atrophy and altered anatomy. This report describes a 23-year-old female with EEC syndrome successfully rehabilitated using a custom-made subperiosteal implant. Despite multiple grafting procedures, conventional implants were not viable. A computer-aided design/computer-aided manufacturing-designed, laser-melted titanium subperiosteal implant was planned based on the cone beam computed tomography imaging and digital scans, ensuring optimal adaptation. At 18 months postsurgery, the implant remained stable, with no complications. This case highlights the potential of modern subperiosteal implants as a viable alternative for complex craniofacial reconstructions.