Hyperbranched molecular structures with potential antiviral activity: derivatives of 5,6-dihydroxyindole-2-carboxylic acid
Articolo
Data di Pubblicazione:
2006
Citazione:
Hyperbranched molecular structures with potential antiviral activity: derivatives of 5,6-dihydroxyindole-2-carboxylic acid / Sechi, Mario; Casu, Fabio; Campesi, Ilaria; Fiori, Stefano; Mariani, Alberto. - In: MOLECULES. - ISSN 1420-3049. - 11:12(2006), pp. 968-977. [10.3390/11120968]
Abstract:
In the search of new HIV-1 integrase (IN) inhibitors, we synthesized a series of multimeric 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives. Preliminary results indicate that hyperbranched architectures could represent a peculiar molecular requisite for the development of new antiviral lead compounds
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Hyperbranched polymers; AB2monomers; DHICA; HIV-1; antiviral agents
Elenco autori:
Sechi, Mario; Casu, Fabio; Campesi, Ilaria; Fiori, Stefano; Mariani, Alberto
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