Reductive Cleavage of Benzannelated Cyclic Ethers and Amines: Synthetic Applications

Articolo

Data di Pubblicazione:

2000

Citazione:

Reductive Cleavage of Benzannelated Cyclic Ethers and Amines: Synthetic Applications / Azzena, Ugo Gavino; Salvatore, Demartis; Luciano, Pilo; Elisabetta, Piras. - In: TETRAHEDRON. - ISSN 0040-4020. - 56:(2000), pp. 8375-8382. [10.1016/S0040-4020(00)00783-3]

Abstract:

Reduction of symmetrical intramolecular diarylmethyl ethers (3a and 8a) and amines (3b and 8b) with alkali metals in THF allows the generation of unsymmetrical oxy- or amino-functionalised arylmethyl organometallics. Such intermediates were successfully trapped with various electrophiles, allowing a new access to unsymmetrically 2,2'-disubstituted-1,1'-biaryls (5aa-5bf) and 1,8-disubstituted naphthalenes

Tipologia CRIS:

1.1 Articolo in rivista

Keywords:

amines; ethers; reductive lithiation

Elenco autori:

Azzena, Ugo Gavino; Salvatore, Demartis; Luciano, Pilo; Elisabetta, Piras

Link alla scheda completa:

https://iris.uniss.it/handle/11388/83767

Pubblicato in:

TETRAHEDRON

Journal