Generation of g-Oxy-Substituted Benzyllithium Derivatives by Reductive Lithiation of 4-Phenyl-1,3-dioxanes

Academic Article

Publication Date:

1999

Short description:

Generation of g-Oxy-Substituted Benzyllithium Derivatives by Reductive Lithiation of 4-Phenyl-1,3-dioxanes / Azzena, U.G., Luciano, P.. - In: SYNTHESIS. - ISSN 0039-7881. - (1999), pp. 664-668.

abstract:

Reductive cleavage of 1,3-dioxanes 1a-c with Li metal in the presence of a catalytic amount of naphthalene in THF, followed by reaction with different electrophiles, allowed the synthesis of 3-substituted- and 3, 3-disubstituted-3-phenylpropan-1-ols 4 in good yields

Iris type:

1.1 Articolo in rivista

Keywords:

reductive lithiation; electron transfer; functionalized carbanions

List of contributors:

Azzena, Ugo Gavino; Luciano, Pilo

Handle:

https://iris.uniss.it/handle/11388/87271

Published in:

SYNTHESIS

Journal