Publication Date:
1997
Short description:
Synthesis of amides with anti-inflammatory and analgesic activities / Pau, Amedeo; Boatto, Gianpiero; Pintore, Giorgio Antonio Mario; Filippelli, Walter; Falcone, Giuseppe; Rossi, Francesco; Palomba, Michele Francesco Luigi; Cerri, Riccardo; Palagiano, Francesco. - In: IL FARMACO. - ISSN 0014-827X. - 52:2(1997), pp. 93-98.
abstract:
A series of N-Aroyl-cyclohexyl- and cyclohexenylamides 3- or 4-methylsubstituted were synthesized and evaluated for their anti-inflammatory and analgesic potencies, and gastrointestinal irritation liability. One compound, N-benzoyl-4-methyl-cyclohexylamide 6a, possessed an anti-inflammatory activity comparable to that of indomethacin.
Iris type:
1.1 Articolo in rivista
Keywords:
Amides; anti-inflammatory activity; analgesic activity
List of contributors:
Pau, Amedeo; Boatto, Gianpiero; Pintore, Giorgio Antonio Mario; Filippelli, Walter; Falcone, Giuseppe; Rossi, Francesco; Palomba, Michele Francesco Luigi; Cerri, Riccardo; Palagiano, Francesco
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