Production and release of antimicrobial and immune defense proteins by mammary epithelial cells following Streptococcus uberis infection of sheep
Academic Article
Publication Date:
2013
Short description:
Production and release of antimicrobial and immune defense proteins by mammary epithelial cells following Streptococcus uberis infection of sheep / Addis, M.f., Pisanu, S., Marogna, G., Cubeddu, T., Pagnozzi, D., Cacciotto, C., Campesi, F., Schianchi, G., Rocca, S., Uzzau, S.. - In: INFECTION AND IMMUNITY. - ISSN 0019-9567. - 81:9(2013), pp. 3182-3197. [10.1128/IAI.00291-13]
abstract:
ABSTRACT Investigating the innate immune response mediators released in milk has
manifold implications, spanning from elucidation of the role played by mammary epithelial
cells (MECs) in fighting microbial infections, to the discovery of novel diagnostic markers for
monitoring udder health in dairy animals. Here, we investigated the mammary gland
response following a two-step experimental infection of lactating sheep with the mastitis-
associated bacterium Streptococcus uberis. The establishment of infection was confirmed ...
manifold implications, spanning from elucidation of the role played by mammary epithelial
cells (MECs) in fighting microbial infections, to the discovery of novel diagnostic markers for
monitoring udder health in dairy animals. Here, we investigated the mammary gland
response following a two-step experimental infection of lactating sheep with the mastitis-
associated bacterium Streptococcus uberis. The establishment of infection was confirmed ...
Iris type:
1.1 Articolo in rivista
Keywords:
MECs; cathelicidins ; S100A9
List of contributors:
Addis, Mf; Pisanu, S; Marogna, G; Cubeddu, T; Pagnozzi, D; Cacciotto, Carla; Campesi, F; Schianchi, G; Rocca, Stefano; Uzzau, Sergio
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