Metal-free mechanochemical oxidations in Ertalyte® jars

The authors acknowledge Form-Tech Scientific for the loan of the FTS-1000 Shaker Mill® apparatus (Form-Tech Scientific, Canada, https://formtechscientific.com/). Authors are grateful to MIUR (Italy, PRIN project: multifunctional polymer composites based on grown materials). A. P. is grateful to MIUR for “Finanziamento delle Attività Base di Ricerca (FABR 2017)“.Aimed at eliminating or at least significantly reducing the use of solvents, sodium hypochlorite pentahydrate crystals (NaOCl·5H2O) in the presence of a catalytic amount of a nitrosyl radical (TEMPO or AZADO) have been successfully used to induce mechanochemical oxidative processes on several structurally different primary and secondary alcohols. The proposed redox process is safe, inexpensive and performing effectively, especially on the macroscale. Herein, an Ertalyte® jar has been successfully used, for the first time, in a mechanochemical process.