Publication Date:
2004
Short description:
Determination of phenol and o-cresol by GC/MS in a fatal poisoning case / Boatto, G., Nieddu, M., Carta, A., Pau, A., Lorenzoni, S., Manconi, P., Serra, D.. - In: FORENSIC SCIENCE INTERNATIONAL. - ISSN 0379-0738. - 139:2 −3(2004), pp. 191-194. [10.1016/j.forsciint.2003.10.023]
abstract:
A fatality due to the ingestion of solution containing phenol and o-cresol is described.The pathological findings were typical
of acute substantial poisoning. Blood, urine and stomach content were obtained during post mortem examinations. Phenol and
o-cresol were identified using GC/MS.The extractions from autopsy materials were obtained as follows: by gel permeation with
cyclohexane/dichloromethane from stomach content, by solid phase extraction (SPE) from urine and by deproteinization with
acetonitrile from blood. The phenol ando-cresol concentrations inthe samples werefound, respectively, asfollows: 115.0and
5.0mg/g in the stomach contents, 58.3 and 1.9mg/ml in the blood, 3.3 and 20.5mg/ml in the urine.
Distributions of phenol in fatal poisonings havebeenreported[J.ForensicSci.27(1982)729;ForensicSci.Int.19(1982)177],
but,usually, colorimetry was used as the analytical method and it cannot exclude the interference ofotherphenolic compounds.
of acute substantial poisoning. Blood, urine and stomach content were obtained during post mortem examinations. Phenol and
o-cresol were identified using GC/MS.The extractions from autopsy materials were obtained as follows: by gel permeation with
cyclohexane/dichloromethane from stomach content, by solid phase extraction (SPE) from urine and by deproteinization with
acetonitrile from blood. The phenol ando-cresol concentrations inthe samples werefound, respectively, asfollows: 115.0and
5.0mg/g in the stomach contents, 58.3 and 1.9mg/ml in the blood, 3.3 and 20.5mg/ml in the urine.
Distributions of phenol in fatal poisonings havebeenreported[J.ForensicSci.27(1982)729;ForensicSci.Int.19(1982)177],
but,usually, colorimetry was used as the analytical method and it cannot exclude the interference ofotherphenolic compounds.
Iris type:
1.1 Articolo in rivista
Keywords:
Phenol; Cresol; Gel permeation; SPE; GC/MS
List of contributors:
Boatto, Gianpiero; Nieddu, M; Carta, Antonio; Pau, Amedeo; Lorenzoni, S; Manconi, P; Serra, D.
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