MicroRNAs as Potential Pharmaco-targets in Ischemia-Reperfusion Injury Compounded by Diabetes
Academic Article
Publication Date:
2019
Short description:
MicroRNAs as Potential Pharmaco-targets in Ischemia-Reperfusion Injury Compounded by Diabetes / Dehaini, H., Awada, H., El-Yazbi, A., Zouein, F.A., Issa, K., Eid, A.A., Ibrahim, M., Badran, A., Baydoun, E., Pintus, G., Eid, A.H.. - In: CELLS. - ISSN 2073-4409. - 8:2(2019), p. 152. [10.3390/cells8020152]
abstract:
Ischemia-Reperfusion (I/R) injury is the tissue damage that results from re-oxygenation of ischemic tissues. There are many players that contribute to I/R injury. One of these factors is the family of microRNAs (miRNAs), which are currently being heavily studied. This review aims to critically summarize the latest papers that attributed roles of certain miRNAs in I/R injury, particularly in diabetic conditions and dissect their potential as novel pharmacologic targets in the treatment and management of diabetes.
Iris type:
1.1 Articolo in rivista
Keywords:
apoptosis; diabetes; ischemia-reperfusion injury; microRNA; pharmaco-targets; reactive oxygen species
List of contributors:
Dehaini, Hassan; Awada, Hussein; El-Yazbi, Ahmed; Zouein, Fouad A; Issa, Khodr; Eid, Assaad A; Ibrahim, Maryam; Badran, Adnan; Baydoun, Elias; Pintus, Gianfranco; Eid, Ali H
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