Selection signatures scan in several Italian sheep breeds identifies genes influencing micronutrient metabolism
Conference Paper
Publication Date:
2018
Short description:
Selection signatures scan in several Italian sheep breeds identifies genes influencing micronutrient metabolism / Sorbolini, S.; Dimauro, C.; Cellesi, M.; Pilla, F.; Macciotta, N. P. P.; Consortium., the BIOVITA. - (2018), p. 151. (Intervento presentato al convegno World Congress on Genetics Applied to Livestock Production tenutosi a Auckland, New Zealand nel 11–16 February 2018).
abstract:
Animal physiological functions involve enzymes and cofactors. Many of these substances can
not be synthesized by the body, but derive from the diet. An example are micronutrients, that
strongly affect production performance, whose requirements are often met by the farmers by
adding supplements to the diet. The aim of this study was to investigate the genetic
variability of Italian sheep breeds searching for possible selective sweeps that harbor genes
involved in the metabolism of micronutrients in. SNP A sample of 496 sheep belonging to 20
breeds farmed in Italy were genotyped with the Illumina Ovine 50K beadchip. Data were
analysed by canonical discriminant analysis (CDA). Forty SNP located in regions of the
genome containing loci involved in the metabolism of vitamins and minerals were detected.
in particular, genes linked to the metabolism of vitamins and minerals such as Selenocysteine
Lyase (SCLY), calcium sensing receptor (CASR), Solute Carrier Family 23 Member 1
(SLC23A1) and Thiamine Triphosphatase (THTPA) were highlighted.
not be synthesized by the body, but derive from the diet. An example are micronutrients, that
strongly affect production performance, whose requirements are often met by the farmers by
adding supplements to the diet. The aim of this study was to investigate the genetic
variability of Italian sheep breeds searching for possible selective sweeps that harbor genes
involved in the metabolism of micronutrients in. SNP A sample of 496 sheep belonging to 20
breeds farmed in Italy were genotyped with the Illumina Ovine 50K beadchip. Data were
analysed by canonical discriminant analysis (CDA). Forty SNP located in regions of the
genome containing loci involved in the metabolism of vitamins and minerals were detected.
in particular, genes linked to the metabolism of vitamins and minerals such as Selenocysteine
Lyase (SCLY), calcium sensing receptor (CASR), Solute Carrier Family 23 Member 1
(SLC23A1) and Thiamine Triphosphatase (THTPA) were highlighted.
Iris type:
4.1 Contributo in Atti di convegno
Keywords:
selection signatures, micronutrients, sheep, Canonical Discriminant Analysis
List of contributors:
Sorbolini, S.; Dimauro, C.; Cellesi, M.; Pilla, F.; Macciotta, N. P. P.; Consortium., the BIOVITA
Book title:
Proceedings of the World Congress on Genetics Applied to Livestock Production