Publication Date:
2007
Short description:
Genetics of psoriasis and psoriatic arthritis / Mathieu, A; Cauli, A; Vacca, A; Mameli, A; Passiu, G; Porru, G; Piga, M; Ibba, V; Mura, V; Sanna, S. - In: REUMATISMO. - ISSN 0048-7449. - 59 Suppl 1:(2007), p. 25-7.
abstract:
Psoriasis and psoriatic arthritis are linked diseases characterised by (distinct ?) immune-mediated pathogenetic mechanisms and by a genetic background interacting with environmental factors. Some candidate susceptibility genes have been studied extensively; they include HLA genes, genes within the HLA region and genes outside the HLA region; among them corneodesmosin and other genes of PSORS1 region, MICA and TNF-a polymorphisms. The main findings in the literature are discussed.
Iris type:
1.1 Articolo in rivista
Keywords:
Alleles; Arthritis, Psoriatic; Genetic Markers; Genetic Predisposition to Disease; Genotype; HLA-C Antigens; Histocompatibility Antigens Class I; Humans; Polymorphism, Genetic; Proteins; Psoriasis; Tumor Necrosis Factor-alpha
List of contributors:
Mathieu, A; Cauli, A; Vacca, A; Mameli, A; Passiu, G; Porru, G; Piga, M; Ibba, V; Mura, V; Sanna, S
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