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EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Rivista
Codice:
E060692
ISSN:
0223-5234
Dati Generali
Dati Generali
Pubblicazioni (55)
Pulisci
Ordina Pubblicazioni:
ascendente
decrescente
2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7trifluoromethylquinoxalines as anticancer agents Inhibitors of folate enzymes
Articolo
3-Aryl-2-[1H-benzotriazol-1-yl]acrylonitriles: A novel classo f potent tubulin inhibitors
Articolo
4-Substituted anilino Imidazo[1,2-a] and triazolo[4,3-a]quinoxalines. Synthesis and evaluation of in vitro biological activity
Articolo
5-Acetyl-2-arylbenzimidazoles as antiviral agents. Part 4.
Articolo
A combined in silico/in vitro approach unveils common molecular requirements for efficient BVDV RdRp binding of linear aromatic N-polycyclic systems
Articolo
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs)
Articolo
A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2′,4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6- tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives.
Articolo
Activity and molecular modeling of a new small molecule active against NNRTI-resistant HIV-1 mutants
Articolo
Adenosiland: Walking through adenosine receptors landscape
Articolo
Antiretroviral activity of metal-chelating HIV-1 integrase inhibitors.
Articolo
Benzotriazole: an overview on its versatile biological behaviour
Articolo
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme
Articolo
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease?
Articolo
Design of novel 3,6-diazabicyclo[3.1.1]heptane derivatives with potent and selective affinities for α4β2 neuronal nicotinic acetylcholine receptors
Articolo
Design, anticancer activity, and mechanistic evaluation of a novel class of selective human carbonic anhydrase IX inhibitors featuring a trifluorodihydroxypropanone pharmacophore
Articolo
Design, anticancer activity, and mechanistic evaluation of a novel class of selective human carbonic anhydrase IX inhibitors featuring a trifluorodihydroxypropanone pharmacophore
Articolo
Design, synthesis and antitubercular activity of 4-alkoxy-triazoloquinolones able to inhibit the M. tuberculosis DNA gyrase
Articolo
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis
Articolo
Development of targeted nanoparticles loaded with antiviral drugs for SARS-CoV-2 inhibition
Articolo
Discovery of novel functionalized 1,2,4-triazoles as PARP-1 inhibitors in breast cancer: Design, synthesis and antitumor activity evaluation
Articolo
Hydroxylated biphenyls as tyrosinase inhibitor: A spectrophotometric and electrochemical study
Articolo
Inhibitors of Yellow Fever Virus replication based on 1,3,5-triphenyl-4,5-dihydropyrazole scaffold: Design, synthesis and antiviral evaluation
Articolo
Inhibitors of Yellow Fever Virus replication based on 1,3,5-triphenyl-4,5-dihydropyrazole scaffold: Design, synthesis and antiviral evaluation
Articolo
Locally constrained xylene-based cyclic mimetics of SOCS3 protein
Articolo
Multi-targeted ChEI-copper chelating molecules as neuroprotective agents
Articolo
Natural products and synthetic analogues against HIV: A perspective to develop new potential anti-HIV drugs
Articolo
New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking
Articolo
Novel 1,3,4-oxadiazole chalcogen analogues: Synthesis and cytotoxic activity
Articolo
Novel inhibitors of AChE and Aβ aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease
Articolo
Novel pyrazole derivatives as neutral CB1 antagonists with significant activity towards food intake
Articolo
Novel substituted quinoxaline 1,4-dioxides with in vitro antimycobacterial and anticandida activity
Articolo
Quinoxaline derivatives as new inhibitors of coxsackievirus B5
Articolo
SYNTHESIS AND KAPPA-BINDING-AFFINITY OF 1-(PYRROLIDIN-1-YLMETHYL)-2-(N-METHYL)-4-[(3,4-DICHLORO)PHENYL]-1,2,3,4- TETRAHYDROISOQUINOLIN-3(2H)-ONES
Articolo
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF 4,4A,5,6-TETRAHYDRO-2H-THIENO[2,3-H]CINNOLIN-3-ONES BIOISOSTERS OF ANTIHYPERTENSIVE AND ANTITHROMBOTIC BENZO[H]CINNOLINONES
Articolo
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF 4,4A-DIHYDRO-5H-[1]BENZOPYRANO[4,3-C]PYRIDAZIN-3(2H)-ONES BIOISOSTERS OF ANTIHYPERTENSIVE AND ANTITHROMBOTIC BENZO[H]CINNOLINONES
Articolo
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF THIENOCINNOLIN-3-(2H)-ONES, BIOISOSTERS OF ANTIHYPERTENSIVE AND ANTITHROMBOTIC BENZO(H)CINNOLINONES
Articolo
SYNTHESIS OF SOME 1-(3-HYDROXY-4-METHOXYBENZYL)-2-ALKYL-6,7-METHYLENEDIOXY-1,2,3,4-TETRAHY DROISOQUINOLINES AND THEIR BINDING AFFINITIES TO DA RECEPTOR SUBTYPES
Articolo
Synthesis and SAR study of novel tricyclic pyrazoles as potent phosphodiesterase 10A inhibitors
Articolo
Synthesis and anti-mycobacterial activities of triazoloquinolones
Articolo
Synthesis and antiproliferative activity of 3-aryl-2-(1H-benzotriazol-1-yl)acrylonitriles. Part III
Articolo
Synthesis and antiproliferative properties of N-3/8-disubstituted 3,8-diazabicyclo[3.2.1]octane analogues of 3,8-bis[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl-piperazine
Articolo
Synthesis and antitubercular activity of 3-aryl substituted-2-(1H(2H)-benzotriazol-1(2)-yl)acrylonitriles
Articolo
Synthesis and antiviral activity of new phenylimidazopyridines and N-benzylidenequinolinamines derived by molecular simplification of phenylimidazo[4,5-g]quinolines
Articolo
Synthesis and biological evaluation of novel delta (δ) opioid receptor ligands with diazatricyclodecane skeletons
Articolo
Synthesis and in vitro antitumor activity of new quinoxaline derivatives
Articolo
Synthesis of N(5,7-diamino-3-phenyl-quinoxalin-2-yl)-3,4,5,-sunstituted anilines and N-[4[(5,7-diamino-3-phenylquinoxalin-2-yl)amino]benzoyl]-L-glutamic acid diethyl ester. Evaluation of in vitro anticancer and antifolate activities
Articolo
Synthesis of antiplatelet activity of some 1,8-Naphthyridine derivates
Articolo
Synthesis, Pharmacological Evaluation and Docking Studies of Pyrrole Structure-Based CB2 Receptor Antagonists
Articolo
Synthesis, anti-mycobacterial, anti-trichomonas and anti-candida in vitro activities of 2-substituted-6,7-difluoro-3-methylquinoxaline 1,4-dioxides
Articolo
Synthesis, cytotoxicity and antiviral evaluation of new series of imidazo[4,5-g]quinoline and pyrido[2,3-g]quinoxalinone derivatives
Articolo
TRICYCLIC 3-(2H)-PYRIDAZINONE DERIVATIVES - SYNTHESIS AND EVALUATION OF THEIR ANTISECRETORY AND ANTIULCER ACTIVITY
Articolo
Triazolopyridinyl-acrylonitrile derivatives as antimicrotubule agents: synthesis, in vitro and in silico characterization of antiproliferative activity, inhibition of tubulin polymerization and binding thermodynamics
Articolo
Tricyclic Pyrazoles. Part 8. Synthesis, Biological Evaluation and Modelling of Tricyclic Pyrazole Carboxamides as Potential CB2 Receptor Ligands with Antagonist/Inverse Agonist Properties.
Articolo
Tricyclic pyrazoles Part 7. Discovery of potent and selective dihydrothienocyclopentapyrazole derived CB2 ligands
Articolo
Tricyclic pyrazoles. Part 6. Benzofuro[3,2-c]pyrazoles: A versatile architecture for CB2 selective ligands
Articolo
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