Data di Pubblicazione:
2005
Citazione:
Synthesis of regiospecifically substituted quinolines from anilines / Chelucci, Giorgio Adolfo; Manca, A.; Pinna, Gerard Aime. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 46:5(2005), pp. 767-770. [10.1016/j.tetlet.2004.12.020]
Abstract:
A protocol for the synthesis of quinolines substituted on both pyridine and benzo-fused rings is reported. The method is
based on the formylation of a substituted N-(tert-butoxycarbonyl)aniline followed by direct cyclisation and aromatisation of the
intermediate product obtained by condensation of the formed N-Boc o-aminobenzaldehyde with an enolisable carbonyl compound.
Yields upto 88% have been obtained.
based on the formylation of a substituted N-(tert-butoxycarbonyl)aniline followed by direct cyclisation and aromatisation of the
intermediate product obtained by condensation of the formed N-Boc o-aminobenzaldehyde with an enolisable carbonyl compound.
Yields upto 88% have been obtained.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Quinolines, Nitrogen heterocycles, Formylation, Azaannulation.
Elenco autori:
Chelucci, Giorgio Adolfo; Manca, A.; Pinna, Gerard Aime
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