Data di Pubblicazione:
2013
Citazione:
The mode of action of anticancer gold-based drugs: a structural perspective / Messori, L; Scaletti, F; Massai, L; Cinellu, Maria Agostina; Gabbiani, C; Vergara, A; Merlino, A.. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - 49:(2013), pp. 10100-10102.
Abstract:
The interactions between a few representative gold-based drugs and
hen egg white lysozyme were studied by X-ray crystallography. High
resolution crystal structures solved for three metallodrug–protein
adducts provide valuable insight into the molecular mechanism
of these promising metal compounds and the inherent protein
metalation processes.
hen egg white lysozyme were studied by X-ray crystallography. High
resolution crystal structures solved for three metallodrug–protein
adducts provide valuable insight into the molecular mechanism
of these promising metal compounds and the inherent protein
metalation processes.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
gold drugs; anticancer drugs; mechanism of action
Elenco autori:
Messori, L; Scaletti, F; Massai, L; Cinellu, Maria Agostina; Gabbiani, C; Vergara, A; Merlino, A.
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