Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against melanoma and non-melanoma skin cancers

Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against melanoma and non-melanoma skin cancers / Roy, Tithi; Boateng, Samuel T.; Banang-Mbeumi, Sergette; Singh, Pankaj K.; Basnet, Pratik; Chamcheu, Roxane-Cherille N.; Ladu, Federico; Chauvin, Isabel; Spiegelman, Vladimir S.; Hill, Ronald A.; Kousoulas, Konstantin G.; Nagalo, Bolni Marius; Walker, Anthony L.; Fotie, Jean; Murru, Siva; Sechi, Mario; Chamcheu, Jean Christopher. - In: BIOORGANIC CHEMISTRY. - ISSN 0045-2068. - 107:(2021), p. 104595. [10.1016/j.bioorg.2020.104595]