Dermination of four thiophenethylamine desigrer drugs (2C-T-series) in human plasma by Capillary Electrophoresis with mass spectrometry detection
Articolo
Data di Pubblicazione:
2007
Citazione:
Dermination of four thiophenethylamine desigrer drugs (2C-T-series) in human plasma by Capillary Electrophoresis with mass spectrometry detection / Boatto, Gianpiero; M., Nieddu; G., Dess; P., Manconi; R., Cerri. - In: JOURNAL OF CHROMATOGRAPHY A. - ISSN 0021-9673. - 1159:1 - 2(2007), pp. 198-202. [10.1016/j.chroma.2006.10.051]
Abstract:
In recent years, the frequent appearance of phenethylamine designer drugs on the illicit drug market has been a matter of concern for all
authorities involved. New phenethylamine drugs are being introduced because these compounds are not covered by existing legislation. Therefore,
the new drugs cannot be considered illicit drugs until their names are officially recognized. This paper describes a method to screen for and
quantify four 2,5-methylenedioxy-derivatives of 4-thio-phenethylamine (2C-T-series) in human plasma, using capillary electrophoresis coupled
with electrospray ionisation-mass spectrometry (CE-ESI-MS). Prior to CE-MS analysis, a simple liquid extraction was used for sample cleanup.
The method was validated according to international guidelines.
authorities involved. New phenethylamine drugs are being introduced because these compounds are not covered by existing legislation. Therefore,
the new drugs cannot be considered illicit drugs until their names are officially recognized. This paper describes a method to screen for and
quantify four 2,5-methylenedioxy-derivatives of 4-thio-phenethylamine (2C-T-series) in human plasma, using capillary electrophoresis coupled
with electrospray ionisation-mass spectrometry (CE-ESI-MS). Prior to CE-MS analysis, a simple liquid extraction was used for sample cleanup.
The method was validated according to international guidelines.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
2C-T-series; 4-Thio-phenylethylamine; Designer drugs; Human plasma; Capillary electrophoresis; Mass-spectrometry
Elenco autori:
Boatto, Gianpiero; M., Nieddu; G., Dess; P., Manconi; R., Cerri
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