Humoral immunity response to HERV-K/W differentiates between amyotrophic lateral sclerosis and other neurological diseases
Articolo
Data di Pubblicazione:
2018
Citazione:
Humoral immunity response to HERV-K/W differentiates between amyotrophic lateral sclerosis and other neurological diseases / Arru, Giannina; Mameli, Giuseppe; Deiana, Giovanni Andrea; Rassu, Anna Laura; Piredda, Rosanna; Sechi, Elia; Caggiu, Elisa; Bo, Marco; Nako, Enri; Urso, Daniele; Mariotto, Sara; Ferrari, Sergio; Zanusso, Gianluigi; Monaco, Salvatore; Sechi, Gianpietro; Sechi, Leonardo A. - In: EUROPEAN JOURNAL OF NEUROLOGY. - ISSN 1351-5101. - 25:8(2018), pp. 1076-1085. [10.1111/ene.13648]
Abstract:
Human endogenous retroviruses-K/W seem play a role in fostering and exacerbation of some neurological diseases, including amyotrophic lateral sclerosis (ALS). Given these findings, we investigated the immunity response against HERV-K and HERV-W envelope surface (env-su) glycoprotein antigens in serum and cerebrospinal fluid (CSF) of ALS, multiple sclerosis (MS) and Alzheimer's disease (AD) patients, and in healthy controls (HCs).
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Alzheimer disease; HERV-K; HERV-W; amyotrophic lateral sclerosis; humoral immunity; multiple sclerosis
Elenco autori:
Arru, Giannina; Mameli, Giuseppe; Deiana, Giovanni Andrea; Rassu, Anna Laura; Piredda, Rosanna; Sechi, Elia; Caggiu, Elisa; Bo, Marco; Nako, Enri; Urso, Daniele; Mariotto, Sara; Ferrari, Sergio; Zanusso, Gianluigi; Monaco, Salvatore; Sechi, Gianpietro; Sechi, Leonardo A
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